Aspergillus fumigatus: virulence genes in a street-smart mold.

  title={Aspergillus fumigatus: virulence genes in a street-smart mold.},
  author={David S. Askew},
  journal={Current opinion in microbiology},
  volume={11 4},
Infections with the filamentous fungus Aspergillus fumigatus are among the most devastating of the systemic mycoses. Unlike most primary pathogens, which possess virulence traits that developed in association with a host organism, evidence suggests that the virulence of A. fumigatus entails a collection of 'street-smart' attributes that have evolved to resist the adverse selection pressures encountered in decaying vegetation. These features enhance the overall competitiveness of the organism in… CONTINUE READING