Aspergillus Fumigatus antigen detection in sera from patients at risk for invasive aspergillosis.

  title={Aspergillus Fumigatus antigen detection in sera from patients at risk for invasive aspergillosis.},
  author={Bernab{\'e} F. F Chumpitazi and Claudine Pinel and Bernadette Lebeau and Pierre Ambroise-Thomas and Ren{\'e}e Grillot},
  journal={Journal of clinical microbiology},
  volume={38 1},
We have developed an inhibition enzyme immunoassay (inhibition-EIA) to monitor for the occurrence of invasive aspergillosis (IA) in sera from 45 immunocompromised (IC) patients. The test uses rabbit polyclonal antibodies and a mixture of components from Aspergillus fumigatus, containing three predominant antigens with molecular weights of 18,000, 33,000, and 56,000. Circulating antigens were found in five of seven proven cases of IA due to A. fumigatus. In two of the five positive cases… CONTINUE READING
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