Asperger syndrome and high functioning autism: research concerns and emerging foci

@article{Blacher2003AspergerSA,
  title={Asperger syndrome and high functioning autism: research concerns and emerging foci},
  author={Jan Blacher and Bonnie R. Kraemer and Monica Schalow},
  journal={Current Opinion in Psychiatry},
  year={2003},
  volume={16},
  pages={535-542}
}
Purpose of review This review focuses on papers that pertain to recent work on Asperger syndrome or high functioning autism. We noted areas in which there was a preponderance of research published over the last year, including: social communication, sensory characteristics, eye gaze, neurocognitive aspects, comorbidity, and treatment and intervention studies. Recent findings Children, adolescents, and even adults with Asperger syndrome/high functioning autism appear to be deficient in social… 

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References

SHOWING 1-10 OF 78 REFERENCES

A Clinical and Neurobehavioural Review of High-Functioning Autism and Asperger's Disorder

TLDR
Neurobehavioural studies, in particular, executive functioning, lateralization, visual-perceptual and motor processing, have provided an important source of information about the potential neurobiological dissociation that may exist between autism and Asperger's disorder.

Comorbidity of Asperger syndrome: a preliminary report.

TLDR
Patients with AS diagnosed according to the ICD-10/DSM-IV criteria presented with symptoms of an additional psychiatric disorder at the time of evaluation or during the 2-year follow-up, while depression was the most common diagnosis in adolescents and adults.

High-functioning autism and schizophrenia: a comparison of an early and late onset neurodevelopmental disorder.

TLDR
It was concluded that individuals with high-functioning autism have a cognitive profile that resembles that of an empirically derived subgroup of schizophrenia patients but that does not resemble profiles found in other schizophrenia subgroups.

Asperger Syndrome and Nonverbal Learning Disabilities

TLDR
Diagnostic confusion and inconsistency has abounded surrounding the concept of Asperger syndrome (AS), as it is now termed; confusion has related not only to the possible overlap of AS and autism, but also between AS and a series of other conditions or diagnostic concepts, many of which are described elsewhere in this volume.

Autism Spectrum Disorders and Low Body Weight: Is There Really a Systematic Association?

TLDR
Although low body weight is often present in male subjects with autism or Asperger syndrome, results indicate that this link is inconsistent and partly mediated by hyperactivity.

Cognitive profiles and social-communicative functioning in children with autism spectrum disorder.

TLDR
Indications of a dissociation between verbal and visual-perceptual skills among the older children, and the specific association of discrepantly high nonverbal skills with increased social symptoms suggest that the nonverbal > verbal profile may index an etiologically significant subtype of autism.

Asperger Syndrome or Autistic Disorder?

TLDR
The purpose of the present article is to provide a brief overview of the diagnostic concept of Asperger syndrome and to help clinicians with diagnostic decisions.

Brain anatomy and sensorimotor gating in Asperger's syndrome.

TLDR
It is hypothesized that Asperger's syndrome is associated with abnormalities in fronto-striatal pathways resulting in defective sensorimotor gating, and consequently characteristic difficulties inhibiting repetitive thoughts, speech and actions.

Head circumference in autism, Asperger syndrome, and ADHD: a comparative study.

TLDR
The hypothesis that children with autistic spectrum disorders often have macrocephalus is tested, and that those without comorbid learning disability are most frequently affected, is found to be correct.
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