Asperger syndrome and high functioning autism: research concerns and emerging foci

  title={Asperger syndrome and high functioning autism: research concerns and emerging foci},
  author={Jan Blacher and Bonnie R. Kraemer and Monica Schalow},
  journal={Current Opinion in Psychiatry},
Purpose of review This review focuses on papers that pertain to recent work on Asperger syndrome or high functioning autism. We noted areas in which there was a preponderance of research published over the last year, including: social communication, sensory characteristics, eye gaze, neurocognitive aspects, comorbidity, and treatment and intervention studies. Recent findings Children, adolescents, and even adults with Asperger syndrome/high functioning autism appear to be deficient in social… 

Second generation antipsychotics in Asperger's Disorder and high functioning autism: a systematic review of the literature and effectiveness of meta-analysis.

There is a lack of robustly conducted trials on the use of SGAs in the management of AD and HFA, so clinicians are cautioned to approach pharmacological treatment prudently balancing benefit with potential cardiometabolic risk.

An event-related source localization study of response monitoring and social impairments in autism spectrum disorder.

It is suggested that reduced ACC activity may reflect a putative brain mechanism involved in the origins and maintenance of social impairments and raise the possibility of the presence of stable brain-behavior relation impairment across development in some individuals with ASD.

Offending in individuals with autistic spectrum disorder : a study of risk and need

Offending in people with Autistic Spectrum Disorder (ASD) though rare requires specialist knowledge of the risk factors involved, to adapt interventions effectively. A review of the somewhat sparse

Growing older with autism: A qualitative study

Experiences of older people with autism were characterised by longing for connection, isolation and loneliness, highlighting the need for greater support for this population with respect to reducing loneliness and improving access to diagnosis.

Cognitive empathy moderates the relationship between affective empathy and wellbeing in adolescents with autism spectrum disorder

Abstract Background: Individuals with autism spectrum disorder (ASD) reportedly have reduced cognitive empathy (CE), yet intact levels of affective empathy (AE) when compared to typically developing

Empathy in Autism Spectrum Disorder

  • Irene E. Harmsen
  • Psychology, Biology
    Journal of autism and developmental disorders
  • 2019
The clinical characteristics and mechanisms underlying empathy in ASD are highlighted by summarizing 61 peer-reviewed articles by providing valuable insights into the roles that genetics, neural networks, and sensory processing have in eliciting empathy.

FOCUS ON PRACTICE: Naturalistic intervention for Asperger syndrome – a case study

A naturalistic multiple-component intervention, making use of social stories, simple peer modelling and individual lessons, appears to be a practical teaching method for inclusive education.

The Efficacy of a Social Skills Group Intervention for Improving Social Behaviors in Children with High Functioning Autism Spectrum Disorders

Examination of the direction and magnitude of change in functioning revealed that children who participated in S.S.GRIN-HFA exhibited significantly greater mastery of social skill concepts compared to children in the control group.



A Clinical and Neurobehavioural Review of High-Functioning Autism and Asperger's Disorder

Neurobehavioural studies, in particular, executive functioning, lateralization, visual-perceptual and motor processing, have provided an important source of information about the potential neurobiological dissociation that may exist between autism and Asperger's disorder.

Comorbidity of Asperger syndrome: a preliminary report.

Patients with AS diagnosed according to the ICD-10/DSM-IV criteria presented with symptoms of an additional psychiatric disorder at the time of evaluation or during the 2-year follow-up, while depression was the most common diagnosis in adolescents and adults.

High-functioning autism and schizophrenia: a comparison of an early and late onset neurodevelopmental disorder.

It was concluded that individuals with high-functioning autism have a cognitive profile that resembles that of an empirically derived subgroup of schizophrenia patients but that does not resemble profiles found in other schizophrenia subgroups.

Asperger Syndrome and Nonverbal Learning Disabilities

Diagnostic confusion and inconsistency has abounded surrounding the concept of Asperger syndrome (AS), as it is now termed; confusion has related not only to the possible overlap of AS and autism, but also between AS and a series of other conditions or diagnostic concepts, many of which are described elsewhere in this volume.

Autism Spectrum Disorders and Low Body Weight: Is There Really a Systematic Association?

Although low body weight is often present in male subjects with autism or Asperger syndrome, results indicate that this link is inconsistent and partly mediated by hyperactivity.

Cognitive profiles and social-communicative functioning in children with autism spectrum disorder.

Indications of a dissociation between verbal and visual-perceptual skills among the older children, and the specific association of discrepantly high nonverbal skills with increased social symptoms suggest that the nonverbal > verbal profile may index an etiologically significant subtype of autism.

Asperger Syndrome or Autistic Disorder?

The purpose of the present article is to provide a brief overview of the diagnostic concept of Asperger syndrome and to help clinicians with diagnostic decisions.

Brain anatomy and sensorimotor gating in Asperger's syndrome.

It is hypothesized that Asperger's syndrome is associated with abnormalities in fronto-striatal pathways resulting in defective sensorimotor gating, and consequently characteristic difficulties inhibiting repetitive thoughts, speech and actions.

Head circumference in autism, Asperger syndrome, and ADHD: a comparative study.

The hypothesis that children with autistic spectrum disorders often have macrocephalus is tested, and that those without comorbid learning disability are most frequently affected, is found to be correct.