Aspects of the role of lecithin:cholesterol acyltransferase in metabolism of triglycerides.

@article{Nordby1978AspectsOT,
  title={Aspects of the role of lecithin:cholesterol acyltransferase in metabolism of triglycerides.},
  author={G L Nordby and Kaare R. Norum},
  journal={Scandinavian journal of clinical and laboratory investigation. Supplementum},
  year={1978},
  volume={150},
  pages={
          111-4
        }
}
  • G L Nordby, Kaare R. Norum
  • Published 1978
  • Chemistry, Medicine
  • Scandinavian journal of clinical and laboratory investigation. Supplementum
  • An increased TG secretion from the liver may lead to an increased secretion of LCAT. Studies on isolated rat hepatocytes have shown: 1. Oleic acid added to the medium stimulates TG and LCAT secretion in a similar way. 2. Cycloheximide, colchicine, 4-amino-pyrazolopyrimidine, and D-galactosamine depress the secretion of both TG and LCAT. 3. There is a positive linear correlation between TG and LCAT secretion in cell preparations from rats operated on with ventromedial hypothalamic lesions… CONTINUE READING