Aspects of rate-related hyperpolarization in feline Purkinje fibers.

  title={Aspects of rate-related hyperpolarization in feline Purkinje fibers.},
  author={Dr. J. Browning and James S Tiedeman and A L Stagg and David G Benditt and Melvin Scheinman and Harold C. Strauss},
  journal={Circulation research},
  volume={44 5},
We studied rate-related hyperpolarization (RRH) in feline Purkinje fibers by standard microelectrode techniques. Restrictions to ionic diffusion are shown to be less in this preparation than in canine preparations. The maximal hyperpolarization (VH) and time constant (T) for the exponentially decaying hyperpolarization following cessation of rapid drive were used as aggregate indices for the underlying rate of sodium pumping, the coupling ratio, and membrane resistance. Changes in VH and T in… CONTINUE READING

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