Aspects of hepatitis C virus infection relating to liver transplantation.

  title={Aspects of hepatitis C virus infection relating to liver transplantation.},
  author={Bruno Roche and Didier Samuel},
  journal={European journal of gastroenterology & hepatology},
  volume={18 4},
End-stage liver disease caused by the hepatitis C virus (HCV) is a major indication for liver transplantation. HCV re-infection after transplantation is almost constant, and recent data confirm that it significantly impairs patient and graft survival. Factors that may influence disease severity and consequent progression of HCV graft injury remain unclear. Chronic HCV infection develops in 75-90% of patients, and 5-30% ultimately progress to cirrhosis within 5 years. Pre-transplantation… CONTINUE READING