Aspects of extracellular matrix remodeling in development and disease.

@article{Holmbeck2006AspectsOE,
  title={Aspects of extracellular matrix remodeling in development and disease.},
  author={Kenn Holmbeck and Ludmila Szabova},
  journal={Birth defects research. Part C, Embryo today : reviews},
  year={2006},
  volume={78 1},
  pages={11-23}
}
The extracellular matrix is the major constituent of organic matter in both plants and animals, where it provides the interface between individual cells. In most tissues, with some notable exceptions such as bone marrow, the volume of extracellular matrix equals or exceeds the volume of intracellular space and organelles, making matrix an abundant constituent through which cells exert their functions and receive cues. The matrix may therefore be considered the basic structural entity that… CONTINUE READING