Aspects of early postnatal development of cortical neurons that proceed independently of normally present extrinsic influences.

Abstract

To examine the contribution of local versus extrinsic influences on postnatal development of cortical neurons, we compared the maturation of deep (infragranular) layer neurons in isolated slices of neocortex grown in organotypic culture to a similar population of neurons developing in vivo. All slice cultures were prepared from sensorimotor cortices of… (More)

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