Aspartic cathepsin D degrades the cytosolic cysteine cathepsin inhibitor stefin B in the cells.

@article{eleznik2015AsparticCD,
  title={Aspartic cathepsin D degrades the cytosolic cysteine cathepsin inhibitor stefin B in the cells.},
  author={Tajana Zajc Železnik and Andrey Kadin and Vito Turk and Iztok Dolenc},
  journal={Biochemical and biophysical research communications},
  year={2015},
  volume={465 2},
  pages={213-7}
}
Stefin B is the major general cytosolic protein inhibitor of cysteine cathepsins. Its main function is to protect the organism against the activity of endogenous potentially hazardous proteases accidentally released from lysosomes. In this study, we investigated the possible effect of endosomal/lysosomal aspartic cathepsins D and E on stefin B after… CONTINUE READING