Aspartate aminotransferase-like immunoreactivity as a marker for aspartate/glutamate in guinea pig photoreceptors

@article{Altschuler1982AspartateAI,
  title={Aspartate aminotransferase-like immunoreactivity as a marker for aspartate/glutamate in guinea pig photoreceptors},
  author={Richard A. Altschuler and Judith L. Mosinger and George G. Harmison and Marianne H. Parakkal and Robert J. Wenthold},
  journal={Nature},
  year={1982},
  volume={298},
  pages={657-659}
}
Immunocytochemical techniques have increased our ability to identify neurones containing a specific neurotransmitter. These techniques could not, however, be applied to two major neurotransmitter candidates, aspartate and glutamate, until our recent study in which aspartate aminotransferase (L-aspartate:2-oxoglutarate aminotransferase, EC 2.6.1.1, AATase) was proposed as a marker1. This enzyme catalyses the reversible reactions of aspartate to oxaloacetate and α-ketoglutarate to glutamate. In… CONTINUE READING