Aspartame and sucrose produce a similar increase in the plasma phenylalanine to large neutral amino acid ratio in healthy subjects.

@article{Burns1991AspartameAS,
  title={Aspartame and sucrose produce a similar increase in the plasma phenylalanine to large neutral amino acid ratio in healthy subjects.},
  author={Thurston S. Burns and W. Wayne Stargel and Carolyn Tschanz and Frank N. Kotsonis and Aryeh Hurwitz},
  journal={Pharmacology},
  year={1991},
  volume={43 4},
  pages={
          210-9
        }
}
  • Thurston S. Burns, W. Wayne Stargel, +2 authors Aryeh Hurwitz
  • Published 1991
  • Chemistry, Medicine
  • Pharmacology
  • Aspartame (L-aspartyl-L-phenylalanine methyl ester) consumption has been postulated to increase brain phenylalanine levels by increasing the molar ratio of the plasma phenylalanine concentration to the sum of the plasma concentrations of the other large neutral amino acids (Phe/LNAA). Dietary manipulations with carbohydrate or protein can also produce changes in the Phe/LNAA value. To compare the effects of aspartame and carbohydrate on Phe/LNAA, beverages sweetened with aspartame, sucrose, and… CONTINUE READING

    Topics from this paper.

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 12 CITATIONS

    Aspartame: A Safety Evaluation Based on Current Use Levels, Regulations, and Toxicological and Epidemiological Studies

    VIEW 1 EXCERPT
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Aspartame's Effects on Behavioral Thermoregulation in Albino Rats

    VIEW 1 EXCERPT
    CITES METHODS

    Aspartame and seizures

    VIEW 2 EXCERPTS
    CITES BACKGROUND

    Non-nutritive Sweeteners and Glycaemic Control

    Review of the nutritional benefits and risks related to intense sweeteners.