Aspartame Sensitivity? A Double Blind Randomised Crossover Study

@article{Sathyapalan2015AspartameSA,
  title={Aspartame Sensitivity? A Double Blind Randomised Crossover Study},
  author={Thozhukat Sathyapalan and Natalie J. Thatcher and Richard Hammersley and Alan S Rigby and Alexandros Pechlivanis and Nigel J. Gooderham and Elaine Holmes and Carel W. le Roux and Stephen L. Atkin and Fraser L. Courts},
  journal={PLoS ONE},
  year={2015},
  volume={10}
}
Background Aspartame is a commonly used intense artificial sweetener, being approximately 200 times sweeter than sucrose. There have been concerns over aspartame since approval in the 1980s including a large anecdotal database reporting severe symptoms. The objective of this study was to compare the acute symptom effects of aspartame to a control preparation. Methods This was a double-blind randomized cross over study conducted in a clinical research unit in United Kingdom. Forty-eight… 

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