Aspartame: A Safety Evaluation Based on Current Use Levels, Regulations, and Toxicological and Epidemiological Studies

  title={Aspartame: A Safety Evaluation Based on Current Use Levels, Regulations, and Toxicological and Epidemiological Studies},
  author={B. Magnuson and G. Burdock and J. Doull and R. Kroes and G. Marsh and M. Pariza and P. Spencer and W. J. Waddell and R. Walker and G. Williams},
  journal={Critical Reviews in Toxicology},
  pages={629 - 727}
Aspartame is a methyl ester of a dipeptide used as a synthetic nonnutritive sweetener in over 90 countries worldwide in over 6000 products. The purpose of this investigation was to review the scientific literature on the absorption and metabolism, the current consumption levels worldwide, the toxicology, and recent epidemiological studies on aspartame. Current use levels of aspartame, even by high users in special subgroups, remains well below the U.S. Food and Drug Administration and European… Expand

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