Asparaginase in the treatment of non-ALL hematologic malignancies


Asparaginases are among the most effective agents against acute lymphoblastic leukemia (ALL) and are Food and Drug Administration-approved for the treatment of pediatric and adult ALL. However, the efficacy of these drugs for the treatment of other hematologic malignancies particularly acute myeloid leukemia is not well established. The mechanism of action… (More)
DOI: 10.1007/s00280-014-2402-3


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