AspC-Mediated Aspartate Metabolism Coordinates the Escherichia coli Cell Cycle

@inproceedings{Liu2014AspCMediatedAM,
  title={AspC-Mediated Aspartate Metabolism Coordinates the Escherichia coli Cell Cycle},
  author={Feng Liu and Qimuge and Jianfeng Hao and Huijuan Yan and Trond Bach and Lifei Fan and Morigen},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND The fast-growing bacterial cell cycle consists of at least two independent cycles of chromosome replication and cell division. To ensure proper cell cycles and viability, chromosome replication and cell division must be coordinated. It has been suggested that metabolism could affect the Escherichia coli cell cycle, but the idea is still lacking solid evidences. METHODOLOGY/PRINCIPLE FINDINGS We found that absence of AspC, an aminotransferase that catalyzes synthesis of aspartate… CONTINUE READING