Asociación entre los polimorfismos de los genes de la enzima convertidora de angiotensina y los receptores AT1R y AT2R y el cáncer de mama: Estudio de casos y controles

@inproceedings{AndrsFelipeCastro2011AsociacinEL,
  title={Asociaci{\'o}n entre los polimorfismos de los genes de la enzima convertidora de angiotensina y los receptores AT1R y AT2R y el c{\'a}ncer de mama: Estudio de casos y controles},
  author={D Andr{\'e}sFelipeCastro and Nelsy Loango and Bayron Alexander Ruiz and Patricia Land{\'a}zuri},
  year={2011}
}
Introduction: breast cancer is the second most common type of cancer and the fifth cause of death due to cancer around the world. The components of the renin-angiotensin system are potential candidates for chemoprevention therapy: the angiotensin converter enzyme (ACE) and type 1 and 2 angiotensin II receptors (AT1R and AT2R).Objective: establishing an association between ACE gene polymorphisms, AT1R and AT2R receptors and breast cancer.Materials and methods: 50 cases and 50 controls were… Expand
Angiotensin Converting Enzyme Insertion/Deletion Polymorphism is Associated with Breast Cancer Risk: A Meta-Analysis
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It is suggested that ACE I/D polymorphism may be associated with increased risk of breast cancer, especially among Asian and Caucasians, however, well-designed studies with larger sample size and more ethnic groups are needed to further validate the results. Expand
Association of ACE I/D, -240A > T and AT1R A1166C polymorphisms with susceptibility to breast cancer: a systematic review and meta-analysis based on 35 case-control studies
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This meta-analysis inconsistence with all previous meta-analyses suggests that the ACE I/D might be associated with BC in overall and by ethnicity. Expand

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