Asiaticoside ameliorates β-amyloid-induced learning and memory deficits in rats by inhibiting mitochondrial apoptosis and reducing inflammatory factors

@inproceedings{Zhang2017AsiaticosideA,
  title={Asiaticoside ameliorates β-amyloid-induced learning and memory deficits in rats by inhibiting mitochondrial apoptosis and reducing inflammatory factors},
  author={Zhuo Zhang and Xiaobin Li and Duo Li and Mao Luo and Yongjie Li and L S Song and Xian Jiang},
  booktitle={Experimental and therapeutic medicine},
  year={2017}
}
The present study aimed to investigate the effects of asiaticoside (AS) on the pathology and associated mechanisms of β-amyloid (Aβ)-induced Alzheimer's disease (AD) in rats. An AD rat model was established by lateral intracerebroventricular injection of Aβ 1-42 oligomers. Learning and memory function were evaluated by Morris water maze (MWM) test. In… CONTINUE READING