Asiatic acid preserves beta cell mass and mitigates hyperglycemia in streptozocin-induced diabetic rats.

@article{Liu2010AsiaticAP,
  title={Asiatic acid preserves beta cell mass and mitigates hyperglycemia in streptozocin-induced diabetic rats.},
  author={Jun Liu and Ting He and Qian Lu and Jing Shang and Hongbin Sun and Luyong Zhang},
  journal={Diabetes/metabolism research and reviews},
  year={2010},
  volume={26 6},
  pages={448-54}
}
BACKGROUND Type 1 diabetes is a chronic condition in which the pancreas produces little or no insulin due to the loss or dysfunction of pancreatic beta cells. This study investigated the beneficial effects of asiatic acid-a triterpenoid compound-preserved beta mass and mitigated hyperglycemia in streptozocin-induced diabetic rats. METHODS Diabetes mellitus was induced in adult male Wistar rats by a single intraperitoneal injection of streptozocin (60 mg/kg body weight). The diabetic rats were… CONTINUE READING
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