Asian Flushing: Genetic and Sociocultural Factors of Alcoholism Among East Asians

@article{Lee2014AsianFG,
  title={Asian Flushing: Genetic and Sociocultural Factors of Alcoholism Among East Asians},
  author={Haeok Lee and S. S. Kim and K. S. You and Wanju Park and J. H. Yang and M. Kim and L. Hayman},
  journal={Gastroenterology Nursing},
  year={2014},
  volume={37},
  pages={327–336}
}
  • Haeok Lee, S. S. Kim, +4 authors L. Hayman
  • Published 2014
  • Medicine
  • Gastroenterology Nursing
  • Alcohol use can lead to a cascade of problems such as increased chances of risky behavior and negative health consequences, including alcoholic liver disease and upper gastric and liver cancer. Ethanol is metabolized mainly by 2 major enzymes: alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH). Genetic variations of genes encoding the 2 enzymes are very common among East Asians but relatively rare for most other populations. Facial flushing and other physical discomforts after… CONTINUE READING
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    • 6

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 69 REFERENCES
    Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men.
    • 606
    Major genetic components underlying alcoholism in Korean population.
    • 64
    • PDF
    Genetic polymorphisms of alcohol and aldehyde dehydrogenases and risk for esophageal and head and neck cancers.
    • 97
    • Highly Influential
    A genome-wide association study of alcohol dependence
    • 485
    • PDF
    ALDH2, ADH1B, and ADH1C Genotypes in Asians: A Literature Review
    • 227
    • Highly Influential
    • PDF
    The Genetics of Alcohol Metabolism: Role of Alcohol Dehydrogenase and Aldehyde Dehydrogenase Variants
    • 485
    • Highly Influential
    • PDF
    Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism.
    • 221
    • PDF