Asialo GM1 is a receptor for Pseudomonas aeruginosa adherence to regenerating respiratory epithelial cells.

@article{Bentzmann1996AsialoGI,
  title={Asialo GM1 is a receptor for Pseudomonas aeruginosa adherence to regenerating respiratory epithelial cells.},
  author={Sophie de Bentzmann and Pierrick Roger and Florence Dupuit and O. Bajolet-laudinat and Claudette Fuchey and M-C. Plotkowski and Edith Puchelle},
  journal={Infection and immunity},
  year={1996},
  volume={64 5},
  pages={
          1582-8
        }
}
We investigated the implication of asialo GM1 as an epithelial receptor in the increased Pseudomonas aeruginosa affinity for regenerating respiratory epithelial cells from cystic fibrosis (CF) and non-CF patients. Human respiratory epithelial cells were obtained from nasal polyps of non-CF subjects and of CF patients homozygous for the delta F 508 transmembrane conductance regulator protein (CFTR) mutation and cultured according to the explant-outgrowth model. At the periphery of the outgrowth… CONTINUE READING

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