• Biology, Computer Science, Medicine
  • Published in Nucleic Acids Research 2008
  • DOI:10.1093/nar/gkn280

AsiDesigner: exon-based siRNA design server considering alternative splicing

@inproceedings{Park2008AsiDesignerES,
  title={AsiDesigner: exon-based siRNA design server considering alternative splicing},
  author={Young-Kyu Park and Seong-Min Park and Young-Chul Choi and Doheon Lee and Misun Won and Young Joo Kim},
  booktitle={Nucleic Acids Research},
  year={2008}
}
RNA interference (RNAi) with small interfering RNA (siRNA) has become a powerful tool in functional and medical genomic research through directed post-transcriptional gene silencing. In order to apply RNAi technique for eukaryotic organisms, where frequent alternative splicing results in diversification of mRNAs and finally of proteins, we need spliced mRNA isoform silencing to study the function of individual proteins. AsiDesigner is a web-based siRNA design software system, which provides… CONTINUE READING

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