Asf1 can promote trimethylation of H3 K36 by Set2.


Asf1 is a conserved histone H3/H4 chaperone that can assemble and disassemble nucleosomes and promote histone acetylation. Set2 is an H3 K36 methyltransferase. The functions of these proteins intersect in the context of transcription elongation by RNA polymerase II: both contribute to the establishment of repressive chromatin structures that inhibit… (More)
DOI: 10.1128/MCB.01229-09


Cite this paper

@article{Lin2010Asf1CP, title={Asf1 can promote trimethylation of H3 K36 by Set2.}, author={Ling-ju Lin and Laura V Minard and Gerald C. Johnston and Richard A. Singer and Michael C. Schultz}, journal={Molecular and cellular biology}, year={2010}, volume={30 5}, pages={1116-29} }