Aseptic meningitis in adult onset Still’s disease
@article{AkkaraVeetil2010AsepticMI, title={Aseptic meningitis in adult onset Still’s disease}, author={Bharath Manu Akkara Veetil and Alan Howe Yee and Kenneth J. Warrington and Allen Jr. Aksamit and Thomas Mason}, journal={Rheumatology International}, year={2010}, volume={32}, pages={4031-4034} }
Adult onset Still’s disease (AOSD) is a systemic inflammatory disease characterized by high-fevers, articular involvement, maculopapular rash, hepatosplenomegaly, lymphadenopathy, and a neutrophilic leukocytosis. Though systemic complications of AOSD or its treatment are well described in the literature, CNS involvement in AOSD is exceedingly rare and can have protean manifestations. We present a patient with AOSD who developed chronic meningitis and sensorineural hearing loss on treatment…
26 Citations
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The case of a 66-year-old male that presents with fever, arthralgia, and laboratory abnormalities suggestive of a systemic inflammatory disease, presenting with neurological manifestations of AOSD is reported.
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The case highlights aseptic meningitis, depression and multiorgan failure as a feature of AOSD/ MAS possibly triggered by ECT, and anakinra is an effective treatment in severe MAS.
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OBJECTIVES
Adult onset Still's disease (AOSD) is a multifactorial systemic autoinflammatory disease. Neurological damage has been scarcely reported in AOSD. We aimed to characterize the clinical…
Non Infectious Cavitary Lung Lesions in a Patient with Adult Onset StillâÂÂsDisease: A Case Report
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This patient was concluded to have noninfectious cavitary lung lesions and discharged home with close follow up, the first patient reported with AOSD Disease without MAS hospitalized for undulating fevers and multiple cavitary Lung lesions without evidence of Tuberculosis of active infection.
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In recent years, anakinra has been used to treat AOSD with promising results and sometimes it is necessary to differentiate from coronary heart disease.
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