Aseptic meningitis in adult onset Still’s disease

@article{AkkaraVeetil2010AsepticMI,
  title={Aseptic meningitis in adult onset Still’s disease},
  author={Bharath Manu Akkara Veetil and Alan Howe Yee and Kenneth J. Warrington and Allen Jr. Aksamit and Thomas Mason},
  journal={Rheumatology International},
  year={2010},
  volume={32},
  pages={4031-4034}
}
Adult onset Still’s disease (AOSD) is a systemic inflammatory disease characterized by high-fevers, articular involvement, maculopapular rash, hepatosplenomegaly, lymphadenopathy, and a neutrophilic leukocytosis. Though systemic complications of AOSD or its treatment are well described in the literature, CNS involvement in AOSD is exceedingly rare and can have protean manifestations. We present a patient with AOSD who developed chronic meningitis and sensorineural hearing loss on treatment… 
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Seizing the clinical presentation in adult onset Still's disease. An extensive literature review.
Neurological manifestations of adult-onset Still’s disease—case-based review
TLDR
The case of a 66-year-old male that presents with fever, arthralgia, and laboratory abnormalities suggestive of a systemic inflammatory disease, presenting with neurological manifestations of AOSD is reported.
Autoimmune meningitis and encephalitis in adult-onset still disease - Case report.
Chronic Fever with Severe Weakness - A Case Report
TLDR
The purpose of this case report is to describe the FUO that can initially mislead diagnosis and to review the literature about AOSD from a primary care perspective.
A comprehensive review on adult onset Still's disease.
Fever of unknown origin: A rheumatologic perspective
TLDR
A case of FUO in a young male adult who was treated several times with antibiotics and anti-malarial with no resolution of symptoms is described and a diagnosis of Adult Onset Still’s Disease (AOSD) was made after thorough investigation.
Electroconvulsive Therapy as a Potential Trigger of Adult Onset StillâÂÂs Disease
TLDR
The case highlights aseptic meningitis, depression and multiorgan failure as a feature of AOSD/ MAS possibly triggered by ECT, and anakinra is an effective treatment in severe MAS.
Adult Onset Still's Disease with Neurological Involvement：A Single Center Report.
OBJECTIVES Adult onset Still's disease (AOSD) is a multifactorial systemic autoinflammatory disease. Neurological damage has been scarcely reported in AOSD. We aimed to characterize the clinical…
Non Infectious Cavitary Lung Lesions in a Patient with Adult Onset StillâÂÂsDisease: A Case Report
TLDR
This patient was concluded to have noninfectious cavitary lung lesions and discharged home with close follow up, the first patient reported with AOSD Disease without MAS hospitalized for undulating fevers and multiple cavitary Lung lesions without evidence of Tuberculosis of active infection.
Intermittent high-spiking fever, muscle and joint pain with sudden chest pain: Adult-onset still's disease?
TLDR
In recent years, anakinra has been used to treat AOSD with promising results and sometimes it is necessary to differentiate from coronary heart disease.
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References

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TLDR
Five episodes of acute neutrophilic meningitis occurring in four female patients with Still’s disease are reported.
Adult onset Still's disease presenting as aseptic meningitis in a young healthy female.
TLDR
This case reveals that AOSD is an important consideration in the differential diagnosis of Aseptic Meningitis Syndrome, and Meningeal signs and abnormal cerebrospinal fluid, both detected in this patient, are very rare occurrences in Still's disease.
Adult onset Still's disease presenting as aseptic meningitis in a young healthy female.
TLDR
This case reveals that AOSD is an important consideration in the differential diagnosis of Aseptic Meningitis Syndrome, and Meningeal signs and abnormal cerebrospinal fluid, both detected in this patient, are very rare occurrences in Still's disease.
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TLDR
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TLDR
The diagnosis of Still's disease is essentially clinical and should not be mistaken for septicemia and high dose steroids treatment can be used in case of systemic involvement.
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TLDR
A patient with adult onset Still's disease who developed meningoencephalitis, sensorimotor peripheral neuropathy and uveitis during the course of disease is described, illustrating the rare occurrence of both central and peripheral neurological involvement in AOSD.
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We describe a unique patient whose clinical and laboratory findings fulfill diagnostic criteria of adult onset Still's disease and at the same time, this case was complicated by aseptic meningitis…
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We describe a 19-year-old woman with hemophagocytic syndrome and adult Still's disease who showed rare features of central neurological involvement, including cerebellar symptoms and the sudden onset…
A case of adult onset Still’s disease with systemic inflammatory response syndrome complicated by fatal status epilepticus
TLDR
A 25-year-old woman with fever lasting over 3 weeks and a fine pink-colored skin rash was diagnosed with AOSD with SIRS complicated by fatal status epilepticus, which led to her death after cardiovascular collapse.
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TLDR
Despite the initial optimism, there is significant long-term morbidity due to recurrent disease flare-ups on the one hand, and articular destructions in some patients on the other.
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