In August 2009, asenapine (Saphris; Schering–Plough) was approved by the US FDA for the acute treatment of schizophrenia and manic or mixed episodes associated with bipolar I disorder in adults. 
DOI: 10.1038/nrd3027


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@article{Meltzer2009Asenapine, title={Asenapine}, author={Herbert Yale Meltzer and Argyris Dritselis and Uma Yasothan and Peter John Kirkpatrick}, journal={Nature Reviews Drug Discovery}, year={2009}, volume={8}, pages={843-844} }