Ascoviruses: superb manipulators of apoptosis for viral replication and transmission.

  title={Ascoviruses: superb manipulators of apoptosis for viral replication and transmission.},
  author={B. Federici and D. Bideshi and Y. Tan and T. Spears and Y. Bigot},
  journal={Current topics in microbiology and immunology},
  • B. Federici, D. Bideshi, +2 authors Y. Bigot
  • Published 2009
  • Medicine, Biology
  • Current topics in microbiology and immunology
  • Ascoviruses are members of a recently described new family (Ascoviridae) of large double-stranded DNA viruses that attack immature stages of insects belonging to the order Lepidoptera, in which they cause a chronic, fatal disease. Ascoviruses have several unusual characteristics not found among other viruses, the most novel of which are their transmission by endoparasitic wasps and a unique cytopathology that resembles apoptosis. Cell infection induces apoptosis and in some species is… CONTINUE READING
    Transcriptome Analyses of Ascovirus Genome Expression in Lepidopteran Larvae and Host Responses


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