Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease.

@article{Levine1996AscorbicAR,
  title={Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease.},
  author={Glenn N. Levine and Balz Frei and Spyridon N Koulouris and Marie D Gerhard and John F. Keaney and Joseph A. Vita},
  journal={Circulation},
  year={1996},
  volume={93 6},
  pages={1107-13}
}
BACKGROUND In the setting of atherosclerosis, endothelial vasomotor function is abnormal. Increased oxidative stress has been implicated as one potential mechanism for this observation. We therefore hypothesized that an antioxidant, ascorbic acid, would improve endothelium-dependent arterial dilation in patients with coronary artery disease. METHODS AND… CONTINUE READING