Ascorbic acid promotes a TGFβ1‐induced myofibroblast phenotype switch

Abstract

l-Ascorbic acid (AA), generally known as vitamin C, is a crucial cofactor for a variety of enzymes, including prolyl-3-hydroxylase (P3H), prolyl-4-hydroxylase (P4H), and lysyl hydroxylase (LH)-mediated collagen maturation. Here, we investigated whether AA has additional functions in the regulation of the myofibroblast phenotype, besides its function in… (More)
DOI: 10.14814/phy2.13324

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