Ascorbic acid modulates cell migration in differentiated HL-60 cells and peripheral blood leukocytes.

@article{Schwager2015AscorbicAM,
  title={Ascorbic acid modulates cell migration in differentiated HL-60 cells and peripheral blood leukocytes.},
  author={Joseph Schwager and Albine Bompard and P. -C. Weber and Daniel G Raederstorff},
  journal={Molecular nutrition & food research},
  year={2015},
  volume={59 8},
  pages={1513-23}
}
SCOPE The impact of L-ascorbic acid (L-AA) on the chemokinesis (CK) and chemotaxis (CT) of HL-60 cells and polymorphonuclear cells (PMN) was investigated. METHODS AND RESULTS HL-60 cells were differentiated with DMSO, retinoic acid (RA), vitamin D, or L-AA. Chemokinesis and chemotaxis of differentiated HL-cells were assayed. Vitamin D3-treated HL-60 cells (dHL-60vitD3 cells) and RA-treated cells (dHL-60RA cells) acquired monocyte/macrophage-like and neutrophil-like phenotypes, respectively… CONTINUE READING
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