Ascorbic acid metabolism and functions: A comparison of plants and mammals

@article{Smirnoff2018AscorbicAM,
  title={Ascorbic acid metabolism and functions: A comparison of plants and mammals},
  author={N. Smirnoff},
  journal={Free Radical Biology & Medicine},
  year={2018},
  volume={122},
  pages={116 - 129}
}
  • N. Smirnoff
  • Published 2018
  • Chemistry, Medicine
  • Free Radical Biology & Medicine
  • &NA; Ascorbic acid is synthesised by eukaryotes, the known exceptions being primates and some other animal groups which have lost functional gulonolactone oxidase. Prokaryotes do not synthesise ascorbate and do not need an ascorbate supply, so the functions that are essential for mammals and plants are not required or are substituted by other compounds. The ability of ascorbate to donate electrons enables it to act as a free radical scavenger and to reduce higher oxidation states of iron to Fe2… CONTINUE READING
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