Ascorbic acid enhances hydroxyl radical formation in iron-fortified infant cereals and infant formulas

@article{Almaas1997AscorbicAE,
  title={Ascorbic acid enhances hydroxyl radical formation in iron-fortified infant cereals and infant formulas},
  author={Runar Almaas and Terje Rootwelt and Stephanie {\O}yas{\ae}ter and Ola D. Saugstad},
  journal={European Journal of Pediatrics},
  year={1997},
  volume={156},
  pages={488-492}
}
Abstract Infant cereals and formulas are usually fortified with iron to prevent iron deficiency. To enhance iron bioavailability, supplemental ascorbic acid is recommended. Ascorbic acid is considered to be an antioxidant in vivo, but has pro-oxidant effects when exposed to non-protein-bound iron. We measured formation of free radicals in cereals and infant formulas after addition of ascorbic acid. The production of hydroxyl radicals was assessed by hydroxylation of salicylic acid to 2,5… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 27 REFERENCES

Effectiveness of iron-forti®ed infant cereal in prevention of iron de®ciency anemia

T Walter, PR Dallman, +7 authors M Arredondo
  • Pediatrics
  • 1993
VIEW 1 EXCERPT

Neonatal oxygen radical disease. In: David TJ (ed) Recent advances in paediatrics

OD Saugstad
  • 1992
VIEW 2 EXCERPTS