Ascorbic Acid and the Common Cold

@article{Pauling1973AscorbicAA,
  title={Ascorbic Acid and the Common Cold},
  author={Linus Carl Pauling},
  journal={Scottish Medical Journal},
  year={1973},
  volume={18},
  pages={1 - 2}
}
  • L. Pauling
  • Published 1 January 1973
  • Medicine, Biology
  • Scottish Medical Journal
An important contribution to the body of evidence about the effectiveness of ascorbic acid (vitamin C) in controlling the common cold has been made by Drs Hume and Weyers on page 3 of this issue of the Scottish Medical Journal in their paper 'Changes in leucocyte ascorbic acid during the common cold'. It has long been recognised that an ascorbic-acid content in leucocytes of 20 ug. or more per 1()8 cells is needed for proper phagocytic activity, and that the amount of ascorbic acid is decreased… 
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Ascorbic acid and the common cold. Evaluation of its efficacy and toxicity.

There is currently little adequate evidence on either the presence or the absence of serious adverse reactions to such doses of ascorbic acid, although many such reactions have been hypothesized.

Vitamin C as a preventive medicine against common colds in children.

Results seemed to indicate that the duration and severity of the cold were reduced while, on the other hand, the incidence remained unaltered or indeed increased, like previously published studies on children.

Vitamin C and Infectious Diseases

The mechanisms whereby vitamin C affects the immune system are poorly understood, although there are reports indicating that it affects the functions of phagocyte functions, the proliferation of T lymphocytes, the production of interferon, and the replication of viruses.

Ascorbic acid and cancer.

Experimental studies suggest that vitamin C may even have an enhancing effect on carcinogenesis and on subsequent developing cancers and the scientific literature on experimental animal studies and cell culture studies has offered only occasional suggestions thatitamin C has an anticancer effect.

Vitamin C and infertility.

Simultaneous Determination of Active Ingredients in Multicomponent Common Over the Counter Tablets in the Present of Parabens and 4-Aminophenol by HPLC

A new selective reverse-phase high-performance liquid chromatography method with an attitude of practical use in pharmaceutical laboratories for simultaneous determination of Ascorbic acid,

Simultaneous Determination of Active Ingredients in Multicomponent Common Over the Counter Tablets in the Present of Parabens and 4-Aminophenol by HPLC

A new selective reverse-phase high-performance liquid chromatography method with an attitude of practical use in pharmaceutical laboratories for simultaneous determination of Ascorbic acid,

References

SHOWING 1-5 OF 5 REFERENCES

Vitamin C and the common cold: a double-blind trial.

It was found that in terms of the average number of colds and days of sickness per subject the vitamin group experienced less illness than the placebo group, but the differences were smaller than have been claimed and were statistically not significant.

Vitamin C and the common cold.

Neither the safety of all dosage forms, nor the efficacy of ascorbic acid in any dosage form, has been proved, and Linus Pauling hopes that there will be a thorough, large-scale study on vitamin C and the common cold.

[Critical evaluation of vitamin C as a prophylactic and therapeutic agent in colds].

Ascorbic acid and infections of the respiratory tract

  • Helvetica Medica Acta,
  • 1961