Ascorbic Acid and the Brain: Rationale for the Use against Cognitive Decline

  title={Ascorbic Acid and the Brain: Rationale for the Use against Cognitive Decline},
  author={F E Harrison and Gene L. Bowman and Maria Cristina Polidori},
This review is focused upon the role of ascorbic acid (AA, vitamin C) in the promotion of healthy brain aging. Particular attention is attributed to the biochemistry and neuronal metabolism interface, transport across tissues, animal models that are useful for this area of research, and the human studies that implicate AA in the continuum between normal cognitive aging and age-related cognitive decline up to Alzheimer's disease. Vascular risk factors and comorbidity relationships with cognitive… CONTINUE READING

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