Ascorbate synthesis-dependent glutathione consumption in mouse liver.

@article{Bnhegyi1996AscorbateSG,
  title={Ascorbate synthesis-dependent glutathione consumption in mouse liver.},
  author={G{\'a}bor B{\'a}nhegyi and Mikl{\'o}s Csala and L{\'a}szl{\'o} Braun and T. Garz{\'o} and J{\^o}zsef Mandl},
  journal={FEBS letters},
  year={1996},
  volume={381 1-2},
  pages={39-41}
}
Ascorbate synthesis causes glutathione consumption in the liver. Addition of gulonolactone resulted in an increase of ascorbate production in isolated murine hepatocytes. At the same time, a decrease in reduced glutathione (GSH) level was observed. In hepatic microsomal membranes, ascorbate synthesis stimulated by gulonolactone caused an almost equimolar… CONTINUE READING