Ascitic fluid and serum from rats with acute pancreatitis injure rat pancreatic tissues and alter the expression of heat shock protein 60

@article{Li2010AsciticFA,
  title={Ascitic fluid and serum from rats with acute pancreatitis injure rat pancreatic tissues and alter the expression of heat shock protein 60},
  author={Yong-yu Li and Xue-jin Li and Shuai Shuai Lv and Kun Li and Yan-na Li and Zhi-Rong Gao and Jia-yan Feng and Chang-jie Chen and Claus Schaefer},
  journal={Cell Stress and Chaperones},
  year={2010},
  volume={15},
  pages={583-591}
}
Acute pancreatitis (AP) is an inflammatory process in which cytokines and chemokines are involved. After onset, extrapancreatic stimuli can induce the expression of cytokines in pancreatic acinar cells, thereby amplifying this inflammatory loop. To further determine the role and mechanism of irritating agents in the pathogenesis of AP, rat pancreatic tissues were stimulated with ascitic fluid (APa) and serum (APs) from rats with AP or with lipopolysaccharide (LPS). In addition, the alteration… CONTINUE READING
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