Ascaridole-less infusions of Chenopodium ambrosioides contain a nematocide ( s ) that is ( are ) not toxic to mammalian smooth muscle

@inproceedings{MacDonalda2004AscaridolelessIO,
  title={Ascaridole-less infusions of Chenopodium ambrosioides contain a nematocide ( s ) that is ( are ) not toxic to mammalian smooth muscle},
  author={D. MacDonalda and K. VanCreyb and P. Harrisonb and P. K. Rangacharia and J. Rosenfeldc and C. Warrend and G. Sorgerd},
  year={2004}
}
  • D. MacDonalda, K. VanCreyb, +4 authors G. Sorgerd
  • Published 2004
Infusions of Chenopodium ambrosioides (L.) have been used for centuries in the Americas as a popular remedy against intestinal worm infections. The essential oil of Chenopodium ambrosioides contains high levels of ascaridole, which is a potent anthelmintic, but which has also been responsible for human fatalities, leading to its disuse. Almost 90% of the nematocidal activity of Chenopodium ambrosioides infusions was due to a hydrophilic component different from ascaridole. Synthetic ascaridole… CONTINUE READING
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