Asbestos-induced changes in rat lung parenchyma.

  • N. F. Johnson
  • Published 1987 in Journal of toxicology and environmental health


Fischer 344 rats have been exposed to UICC crocidolite by whole-body inhalation procedures for periods of 1 d to 12 mo. Material was obtained from the same location in the left lung, and the numbers of cells in the parenchyma were identified and determined by transmission electron microscopy. An immediate increase (1 d of exposure) was evident in the number… (More)