As an independent prognostic factor, FAT10 promotes hepatitis B virus-related hepatocellular carcinoma progression via Akt/GSK3β pathway

@article{Liu2014AsAI,
  title={As an independent prognostic factor, FAT10 promotes hepatitis B virus-related hepatocellular carcinoma progression via Akt/GSK3β pathway},
  author={L. Liu and Zizheng Dong and Jin-Tung Liang and Carolyn Cao and Jiazhi Sun and Y Ding and D Wu},
  journal={Oncogene},
  year={2014},
  volume={33},
  pages={909-920}
}
FAT10 is an oncogene that is localized at 6q21.3, a region frequently amplified in hepatocellular carcinoma (HCC). Recently, growing attention has been paid to its effect in the initiation of various cancers. However, there has been little research into the influence of FAT10 on the progression and prognosis of HCC, especially in hepatitis B virus (HBV)-related HCC. Here, we aimed at investigating clincopathological significance of FAT10 in HBV-related HCC and its underlying mechanisms. Based… CONTINUE READING

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