Arylsulfatase A in pseudodeficiency

@article{Herz2004ArylsulfataseAI,
  title={Arylsulfatase A in pseudodeficiency},
  author={Barbara Herz and Gideon Bach},
  journal={Human Genetics},
  year={2004},
  volume={66},
  pages={147-150}
}
SummaryArylsulfatase A (ASA) is found to be deficient in healthy individuals (pseudo arylsulfatase A deficiency) who usually show in vitro ASA levels in the range of metachromatic leukodystrophy patients. The in vitro properties of ASA in pseudodeficiency were studied in cultured fibroblasts. The residual ASA activity showed apparent Km with the synthetic substrate (2.6mM), pH optimum of activity (pH 5.0), and sensitivity to heat denaturation at 65°C (T1/2, 10 min) similar to those found in… Expand
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