Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries.

@article{Tijet2006ArylHR,
  title={Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries.},
  author={Nathalie Tijet and Paul C. Boutros and Ivy D. Moffat and Allan B. Okey and Jouko Tuomisto and Raimo Pohjanvirta},
  journal={Molecular pharmacology},
  year={2006},
  volume={69 1},
  pages={
          140-53
        }
}
Conventional biochemical and molecular techniques identified previously several genes whose expression is regulated by the aryl hydrocarbon receptor (AHR). We sought to map the complete spectrum of AHR-dependent genes in male adult liver using expression arrays to contrast mRNA profiles in Ahr-null mice (Ahr(-/-)) with those in mice with wild-type AHR (Ahr(+)(/)(+)). Transcript profiles were determined both in untreated mice and in mice treated 19 h earlier with 1000 microg/kg 2,3,7,8… CONTINUE READING
Highly Influential
This paper has highly influenced 21 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 215 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 112 extracted citations

Dioxin-Dependent and Dioxin-Independent Gene Batteries: Comparison of Liver and Kidney in AHR-Null Mice

Toxicological sciences : an official journal of the Society of Toxicology • 2009
View 7 Excerpts
Method Support
Highly Influenced

Aryl hydrocarbon receptor-dependent induction of flavin-containing monooxygenase mRNAs in mouse liver.

Drug metabolism and disposition: the biological fate of chemicals • 2008
View 11 Excerpts
Highly Influenced

215 Citations

0102030'08'11'14'17
Citations per Year
Semantic Scholar estimates that this publication has 215 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 42 references

A novel induction mechanism of the rat CYP1A2 gene mediated by Ah receptor-Arnt heterodimer.

Biochemical and biophysical research communications • 2004
View 4 Excerpts
Highly Influenced

Dioxin-responsive AHRE-II gene battery: identification by phylogenetic footprinting.

Biochemical and biophysical research communications • 2004
View 6 Excerpts
Highly Influenced

Summaries of Affymetrix GeneChip probe level data.

Nucleic acids research • 2003
View 2 Excerpts
Highly Influenced