Aryl Hydrocarbon Receptor Regulates Distinct Dioxin-Dependent and Dioxin-Independent Gene Batteries

@article{Tijet2006ArylHR,
  title={Aryl Hydrocarbon Receptor Regulates Distinct Dioxin-Dependent and Dioxin-Independent Gene Batteries},
  author={Nathalie Tijet and Paul C. Boutros and Ivy D. Moffat and Allan B. Okey and Jouko Tuomisto and Raimo Pohjanvirta},
  journal={Molecular Pharmacology},
  year={2006},
  volume={69},
  pages={140 - 153}
}
Conventional biochemical and molecular techniques identified previously several genes whose expression is regulated by the aryl hydrocarbon receptor (AHR). We sought to map the complete spectrum of AHR-dependent genes in male adult liver using expression arrays to contrast mRNA profiles in Ahr-null mice (Ahr–/–) with those in mice with wild-type AHR (Ahr+/+). Transcript profiles were determined both in untreated mice and in mice treated 19 h earlier with 1000 μg/kg 2,3,7,8-tetrachlorodibenzo-p… Expand
Dioxin-Dependent and Dioxin-Independent Gene Batteries: Comparison of Liver and Kidney in AHR-Null Mice
TLDR
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TLDR
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TLDR
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