• DOI:10.1124/mol.105.018705
Corpus ID: 1913812

Aryl Hydrocarbon Receptor Regulates Distinct Dioxin-Dependent and Dioxin-Independent Gene Batteries

@article{Tijet2006ArylHR,
  title={Aryl Hydrocarbon Receptor Regulates Distinct Dioxin-Dependent and Dioxin-Independent Gene Batteries},
  author={N. Tijet and P. Boutros and I. Moffat and A. Okey and J. Tuomisto and R. Pohjanvirta},
  journal={Molecular Pharmacology},
  year={2006},
  volume={69},
  pages={140 - 153}
}

N. Tijet, P. Boutros, +3 authors R. Pohjanvirta

Published 2006

Biology, Medicine

Molecular Pharmacology

Conventional biochemical and molecular techniques identified previously several genes whose expression is regulated by the aryl hydrocarbon receptor (AHR). We sought to map the complete spectrum of AHR-dependent genes in male adult liver using expression arrays to contrast mRNA profiles in Ahr-null mice (Ahr–/–) with those in mice with wild-type AHR (Ahr+/+). Transcript profiles were determined both in untreated mice and in mice treated 19 h earlier with 1000 μg/kg 2,3,7,8-tetrachlorodibenzo-p… CONTINUE READING

View on ASPET

molpharm.aspetjournals.org

Save to Library

Create Alert

Cite

Launch Research Feed