Arundic acid (ONO-2506) inhibits secondary injury and improves motor function in rats with spinal cord injury.

Abstract

BACKGROUND Arundic acid (ONO-2506) inhibits the production and release of S100 protein from astrocytes. While numerous studies have assessed the effect of ONO-2506 in the diseased brain, to the best of our knowledge, no study has examined the effect of ONO-2506 in spinal cord injury (SCI). In this study, we administered ONO-2506 to rats with SCI in order to… (More)
DOI: 10.1016/j.jns.2013.12.008

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