Artiodactyl emergence is accompanied by the birth of an extensive pool of diverse germline TRDV1 genes

Abstract

Molecular cloning of cDNA from γ/δ T cells has shown that in sheep, the variable domain of the δ chain is chiefly determined by the expression of the TRDV1 subgroup, apparently composed of a large number of genes. There are three other TRDV subgroups, but these include only one gene each. To evaluate the extent and the complexity of the genomic TRDV… (More)
DOI: 10.1007/s00251-005-0773-7

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