• Corpus ID: 8356801

Artificial sweeteners: safe or unsafe?

@article{QurratUlAin2015ArtificialSS,
  title={Artificial sweeteners: safe or unsafe?},
  author={Qurrat-Ul-Ain and Sohaib Ahmed Khan},
  journal={JPMA. The Journal of the Pakistan Medical Association},
  year={2015},
  volume={65 2},
  pages={
          225-7
        }
}
  • Qurrat-Ul-AinS. Khan
  • Published 1 February 2015
  • Medicine
  • JPMA. The Journal of the Pakistan Medical Association
Artificial sweeteners or intense sweeteners are sugar substitutes that are used as an alternative to table sugar. They are many times sweeter than natural sugar and as they contain no calories, they may be used to control weight and obesity. Extensive scientific research has demonstrated the safety of the six low-calorie sweeteners currently approved for use in foods in the U.S. and Europe (stevia, acesulfame-K, aspartame, neotame, saccharin and sucralose), if taken in acceptable quantities… 

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References

SHOWING 1-10 OF 15 REFERENCES

Sugar substitutes: Health controversy over perceived benefits

  • K. Tandel
  • Medicine
    Journal of pharmacology & pharmacotherapeutics
  • 2011
The health controversy over perceived benefits of sugar substitutes is explored, with conclusions ranging from “safe under all conditions” to “unsafe at any dose”.

Artificial sweeteners--do they bear a carcinogenic risk?

  • M. WeihrauchV. Diehl
  • Medicine
    Annals of oncology : official journal of the European Society for Medical Oncology
  • 2004
According to the current literature, the possible risk of artificial sweeteners to induce cancer seems to be negligible and epidemiological studies in humans did not find the bladder cancer-inducing effects of saccharin and cyclamate that had been reported from animal studies in rats.

Nonnutritive Sweeteners: Current Use and Health Perspectives A Scientific Statement From the American Heart Association and the American Diabetes Association

The present statement from the American Heart Association and the American Diabetes Association addresses the potential role of nonnutritive sweeteners (NNS) in helping Americans to adhere to population-wide reductions in added sugars intake in the context of current usage and health perspectives.

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

It is demonstrated that consumption of commonly used NAS formulations drives the development of glucose intolerance through induction of compositional and functional alterations to the intestinal microbiota, thereby calling for a reassessment of massive NAS usage.

Association between intake of artificially sweetened and sugar-sweetened beverages and preterm delivery: a large prospective cohort study.

Intakes of both As and SS beverages increased with increasing BMI and energy intake and were higher in women with less education, in daily smokers, and in single women, suggesting that a high intake of both AS and SS beverage is associated with an increased risk of preterm delivery.

A role for sweet taste: calorie predictive relations in energy regulation by rats.

Reducing the correlation between sweet taste and the caloric content of foods using artificial sweeteners in rats resulted in increased caloric intake, increased body weight, and increased adiposity, as well as diminished caloric compensation and blunted thermic responses to sweet-tasting diets.

Fueling the Obesity Epidemic? Artificially Sweetened Beverage Use and Long‐term Weight Gain

The question whether AS use might be fueling—rather than fighting—the authors' escalating obesity epidemic is raised, as a significant positive dose‐response relationship emerged between baseline ASB consumption and all outcome measures, adjusted for baseline BMI and demographic/behavioral characteristics.

Effects of dietary iron and folate supplementation on the physiological changes produced in weanling rats by sodium saccharin exposure.

  • E. GarlandR. Shapiro S. Cohen
  • Medicine
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1993