Artificial selection for intrinsic aerobic endurance running capacity in rats.

  title={Artificial selection for intrinsic aerobic endurance running capacity in rats.},
  author={Lauren G Koch and Steven Loyal Britton},
  journal={Physiological genomics},
  volume={5 1},
Artificial selection for intrinsic aerobic endurance running capacity was started using genetically heterogeneous N:NIH stock of rats as a founder population (n = 168). Selection for low and high capacity was based upon distance run to exhaustion on a motorized treadmill using a velocity-ramped running protocol. The starting velocity was 10 m/min and was increased by 1 m/min every 2 min (slope was constant at 15 degrees ). At each generation, within-family selection was practiced using 13… CONTINUE READING
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