Artificial rearing of infant rats on milk formula deficient in n-3 essential fatty acids: A rapid method for the production of experimental n-3 deficiency

@article{Ward1996ArtificialRO,
  title={Artificial rearing of infant rats on milk formula deficient in n-3 essential fatty acids: A rapid method for the production of experimental n-3 deficiency},
  author={Glenn Ward and James Woods and Michelle L. Reyzer and Norman Salem},
  journal={Lipids},
  year={1996},
  volume={31},
  pages={71-77}
}
Research into the function of docosahexaenoic acid (DHA; 22:6n-3), the predominant polyunsaturated fatty acid (PUFA) in the central nervous system (CNS), is often hindered by the difficulty in obtaining dramatic experimental decreases in DHA in the brain and retina of laboratory rats. In this study, the artificial rearing procedure, whereby infant rats are removed from their mothers, gastrostomized, and fed synthetic formula, was used in an attempt to produce rapid changes in CNS levels of DHA… CONTINUE READING