Artificial promoters for metabolic optimization.

  title={Artificial promoters for metabolic optimization.},
  author={Peter Ruhdal Jensen and K. Hammer},
  journal={Biotechnology and bioengineering},
  volume={58 2-3},
In this article, we review some of the expression systems that are available for Metabolic Control Analysis and Metabolic Engineering, and examine their advantages and disadvantages in different contexts. In a recent approach, artificial promoters for modulating gene expression in micro-organisms were constructed using synthetic degenerated oligonucleotides. From this work, a promoter library was obtained for Lactococcus lactis, containing numerous individual promoters and covering a wide range… CONTINUE READING

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