Artificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines.

Abstract

Recent studies demonstrate that virus-cellular receptor interactions are not the sole determinants of adenovirus (Ad) tropism. It has been shown that the fiber shaft length, which ranges from 6 to 23 beta-repeats in human Ads, also influences viral tropism. However, there is no report that investigates whether artificial extension of the shaft alters the… (More)

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Cite this paper

@article{Seki2002ArtificialEO, title={Artificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines.}, author={Toshiro Seki and I. A. Dmitriev and Elena A. Kashentseva and Koichi Takayama and Marianne G. Rots and Kaori Suzuki and David Curiel}, journal={Journal of virology}, year={2002}, volume={76 3}, pages={1100-8} }