Artificial Neural Network Modification of Simulation-Based Fitting: Application to a Protein-Lipid System

@article{Nazarov2004ArtificialNN,
  title={Artificial Neural Network Modification of Simulation-Based Fitting: Application to a Protein-Lipid System},
  author={Petr V. Nazarov and Vladimir V. Apanasovich and Vladimir M. Lutkovski and Mikalai M. Yatskou and Rob B. M. Koehorst and Marcus A. Hemminga},
  journal={Journal of chemical information and computer sciences},
  year={2004},
  volume={44 2},
  pages={
          568-74
        }
}
Simulation-based fitting has been applied to data analysis and parameter determination of complex experimental systems in many areas of chemistry and biophysics. However, this method is limited because of the time costs of the calculations. In this paper it is proposed to approximate and substitute a simulation model by an artificial neural network during the fitting procedure. Such a substitution significantly speeds up the parameter determination. This approach is tested on a model of… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 20 REFERENCES

Energy transfer processes in zinc porphyrin films studied by time - resolved fluorescence spectroscopy and Monte Carlo simulations

M. M. Yatskou, H. Donker, R. B. M. Koehorst, A. van Hoek, T. J. Schaafsma
  • Chem . Phys . Lett .
  • 2001

Energy transfer processes in zinc porphyrin films studied by time - resolved fluorescence spectroscopy and Monte Carlo simulations

M. M. Yatskou, H. Donker, R. B. M. Koehorst, A. van Hoek, T. J. Schaafsma
  • Chem . Phys . Lett .
  • 2001

Nonisotropic excitation energy transport in organized molecular systems : Monte Carlo simulation - based analysis of time - resolved fluorescence

M. M. Yatskou, H. Donker, +4 authors T. J. Schaafsma
  • J . Phys . Chem . A
  • 2001

Nonisotropic excitation energy transport in organized molecular systems : Monte Carlo simulation - based analysis of time - resolved fluorescence

M. M. Yatskou, H. Donker, +4 authors T. J. Schaafsma
  • J . Phys . Chem . A
  • 2001

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