Artificial Blood

@article{Squires2002ArtificialB,
  title={Artificial Blood},
  author={Jerry E. Squires},
  journal={Science},
  year={2002},
  volume={295},
  pages={1002 - 1005}
}
Blood substitutes are under development for transfusion in place of donor blood during emergencies and lengthy surgeries. The first generation of blood substitutes is currently in clinical trials. 

Paper Mentions

News Article
Artificial Blood: A Futuristic Dimension of Modern Day Transfusion 
Sciences
TLDR
Artificial blood can complement the current blood products for transfusion and create a stable supply of safe and effective products to reduce the requirements of blood transfusions drastically especially in settings of trauma and surgery thereby reducing the reliance on banked donated blood. Expand
2017 Military Supplement: Hemoglobin-based Oxygen Carriers: Current State-of-the-Art and Novel Molecules.
TLDR
A comprehensive review of Hb-based oxygen carriers (HBOCs) is provided, including current state-of-the-art and novel molecules in development, along with a critical discussion of successes and challenges in this field. Expand
Hemoglobin coated oxygen storage metal-organic framework as a promising artificial oxygen carrier.
  • Qi Wang, J. Gong, +5 authors Li Wu
  • Medicine
  • Journal of materials chemistry. B
  • 2021
TLDR
The sustained electrochemical responses toward H2O2 and O2 make the Hemoglobin-functionalized HKUST-1 an ideal candidate as a promising artificial blood substitute. Expand
The Impact of Direct Cash Payments on Whole Blood Supply
Abstract This paper investigates the impact of monetary incentives on whole blood donations. We take advantage of a quasi-natural experiment in Germany, in which one blood donation site changes itsExpand
To study the effect of oxygen carrying capacity on expressed changes of erythrocyte membrane protein in different storage times
TLDR
This research collected 30 cases of healthy blood donors, and explored erythrocyte stored at different times relating indicators including effective oxygen uptake (Q), P50, 2,3-DPG, Na+-k+-ATP, and expression changes of membrane protein EPB41, S1P, GLTP, SPPL2A resulting in the expression change of ery Throcyte surface membrane protein. Expand
Nanomaterials for Tumor Hypoxia Relief to Improve the Efficacy of ROS-Generated Cancer Therapy
TLDR
An overview of current nanomaterial-based strategies for advanced cancer therapy by modulating the hypoxia in the TME and promoting ROS generation, with particular emphasis on the O2 supply capability and mechanism of these nanoplatforms. Expand
Perfluorocarbon nanoemulsion promotes the delivery of reducing equivalents for electricity-driven microbial CO2 reduction
Combining inorganic catalysts with CO2-fixing microorganisms has displayed a high efficiency for electricity-driven CO2 reduction. However, the maximum throughput can be limited by the low solubilityExpand
Emergent Fluorous Molecules and Their Uses in Molecular Imaging.
TLDR
This Account describes new families of fluorous molecules, such as chelators, fluorophores, and peptides, that are soluble in FC oils that have helped transform the field of in vivo molecular imaging by enabling sensitive and cell-specific imaging using magnetic resonance imaging, positron emission tomography, and fluorescence detection. Expand
Metallofluorocarbon Nanoemulsion for Inflammatory Macrophage Detection via PET and MRI
TLDR
Multimodal detection using FERM yields robust whole-body lesion detection and leverages the strengths of combined PET and 19F MRI and is potentially useful for precise diagnosis, stratification, and treatment monitoring of inflammatory diseases. Expand
Ultrasound-Guided Cytosolic Protein Delivery via Transient Fluorous Masks.
The inability to spatiotemporally guide proteins in tissues, and efficiently deliver them into cells, remain key barriers to realizing their full potential in precision medicine. Here, we reportExpand
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