Articular cartilage vesicles generate calcium pyrophosphate dihydrate-like crystals in vitro.

@article{Derfus1992ArticularCV,
  title={Articular cartilage vesicles generate calcium pyrophosphate dihydrate-like crystals in vitro.},
  author={Beth A Derfus and John W Rachow and Neil S Mandel and Adele Ludin Boskey and M A Buday and Vladimir M. Kushnaryov and Lawrence M. Ryan},
  journal={Arthritis and rheumatism},
  year={1992},
  volume={35 2},
  pages={231-40}
}
OBJECTIVE To identify the morphology of a mineral-forming of adult porcine hyaline articular cartilage digest and characterize the mineral it forms. METHODS Electron microscopy, Fourier transform infrared (FTIR) spectroscopy, x-ray microanalysis, compensated polarized light microscopy, and biochemical studies including 14C-labeled UDPG pyrophosphohydrolase radiometric assay. RESULTS This fraction of articular cartilage digest contained membrane-limited vesicles resembling growth plate… CONTINUE READING

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